Aqueous Extract Of Tutsan (Hypericum Androsaemum L.) Red Berries Exhibits Antioxidant Activity And Effects Akin To Those Of An Antidepressant
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Abstract
Hypericum androsaemum L., sometimes referred to as "tutsan" or "shrubby St. John's Wort," is a plant in the Hypericum genus that grows naturally in the Mediterranean region. It is widely grown as an ornamental plant because of the striking color variation in its young, berry-like capsules, which turn shiny black as they ripen from red. In traditional medicine from Portugal and Spain, tutsan has also been used to treat depression. We evaluated the potential benefits of H. androsaemum red berry water extract (WE). After H. androsaemum red berries were decocted, WE was produced, and its ten bioactive component content was ascertained using HPLC-DAD analysis. By boosting endogenous antioxidant defenses and restoring normal behavior, the maximum dosage of WE was found to effectively alleviate the symptoms of depression overall and lower oxidative stress levels.
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