Pharmacological Assessment of The Ethanolic extract of Alpinia Calcarata Rhizome For Anti-Inflammatory and Antioxidant Activities
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Abstract
To evaluate the antibacterial activity and chemical constituents of the essential oil from the Artemisia argyi grown in Qichun (China). Alpinia calcarata rhizome ethanolic extract was tested for anti-asthmatic, antioxidant, and anti-inflammatory properties. Adaptogens normalize leukocytosis after milk consumption. Eosinophils are necessary for allergic illness development. The plant extract significantly reduced allergic asthmarelated eosinophil cell count compared to the control group. Eosinophil count decreases cell recruitment and IL-4, IL-5, and IL-13, which affect cell count. Studies on milk-induced leukocytosis and eosinophils verified the plant extract's anti-asthmatic capabilities. In guinea pigs, goats, horses, dogs, and humans, histamine contracts trachea and bronchial muscles. Tracheas in guinea pigs test asthma drugs.Gas chromatography-mass spectrometry(GC-MS),DPPH,ABTS was applied for the identification of chemical constituents in volatile oil from Artemisia argyi and the relative percentage of each component was calculated by area normalization. The study of investigation showed that the ethanolic extract of Alpinia Calcarata rhizomes possess The antioxidant and anti- inflammatory property of the plant also supports its anti-asthmatic property. Drugs effective in asthma are mostly steroidal in nature. Phytochemical analysis showed presence of flavonoid and steroids. The anti-asthmatic property showed by the plant may be because of these chemical moieties. The results obtained in the study supports the traditional and also demands further research and to isolate and characterize active principles responsible for The antioxidant and anti- inflam
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