INVESTIGATION OF THE FREQUENCY OF CONTAMINATION OF THE ORAL CAVITY WITH CANDIDA FUNGI AND THEIR SENSITIVITY TO ANTIFUNGAL DRUGS IN CHILDREN WITH BRONCHIAL ASTHMA WHO USE INHALED GLUCOCORTICOSTEROIDS FOR A LONG TIME

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Mutalimova Liana Rashidovna
Garunova Azinat Ullubievna
Eminova Kamila Isrefilovna
Alimetova Saida Magomedagaevna
Abdulkadyrov Anvar Muradovich
Kurbanalieva Zarema Abdullaevna
Abdullaeva Leila Elmanovna
Musaeva Ramilya Nadirovna
Omarova Izabella Ruslanovna
Dalgatov Sultan Inzhalupovich
Omargadjieva Aminat Shamilovna

Abstract

Bronchial asthma is a chronic inflammatory disease of the respiratory tract that causes the development of bronchial hyperreactivity, which leads to repeated episodes of wheezing, expiratory shortness of breath, chest congestion and coughing, increasing at night or early in the morning. The main groups of drugs for the basic therapy of bronchial asthma are inhaled glucocorticosteroids in the form of individual drugs or in combination with anticholinergic or B-2 agonists. Preparations of inhaled glucocorticosteroids have a number of side effects, one of which is oropharyngeal candidiasis, which often occurs according to a number of instructions (>1/100,<1/10). This is due to the fact that inhaled glucocorticosteroids create favorable conditions for the growth of yeast-like fungi of the genus Candida in the oral cavity and pharynx, due to the suppression of the protective functions of macrophages, neutrophils and T-lymphocytes on the surface of the oral mucosa, as well as due to the appearance of dryness of the oral cavity. In this connection, IGCS preparations have instructions for use. Namely, taking into account the risk of oropharyngeal candidiasis, the patient should thoroughly rinse his mouth with water after each inhalation of the drug. The purpose of the study is to study the awareness of patients about the prevention and risks of fungal infections of the oral cavity arising from the use of inhaled glucocorticosteroids.

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How to Cite
Mutalimova Liana Rashidovna, Garunova Azinat Ullubievna, Eminova Kamila Isrefilovna, Alimetova Saida Magomedagaevna, Abdulkadyrov Anvar Muradovich, Kurbanalieva Zarema Abdullaevna, Abdullaeva Leila Elmanovna, Musaeva Ramilya Nadirovna, Omarova Izabella Ruslanovna, Dalgatov Sultan Inzhalupovich, & Omargadjieva Aminat Shamilovna. (2024). INVESTIGATION OF THE FREQUENCY OF CONTAMINATION OF THE ORAL CAVITY WITH CANDIDA FUNGI AND THEIR SENSITIVITY TO ANTIFUNGAL DRUGS IN CHILDREN WITH BRONCHIAL ASTHMA WHO USE INHALED GLUCOCORTICOSTEROIDS FOR A LONG TIME. Journal for ReAttach Therapy and Developmental Diversities, 7(6), 62–65. https://doi.org/10.53555/jrtdd.v7i6.3033
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Author Biographies

Mutalimova Liana Rashidovna

Federal State Budgetary Educational Institution of Higher Education "Dagestan State Medical University" of the Ministry of Health of the Russian Federation

Garunova Azinat Ullubievna

Federal State Budgetary Educational Institution of Higher Education "Dagestan State Medical University" of the Ministry of Health of the Russian Federation

Eminova Kamila Isrefilovna

Federal State Budgetary Educational Institution of Higher Education "Dagestan State Medical University" of the Ministry of Health of the Russian Federation

Alimetova Saida Magomedagaevna

Federal State Budgetary Educational Institution of Higher Education "Dagestan State Medical University" of the Ministry of Health of the Russian Federation

Abdulkadyrov Anvar Muradovich

Federal State Budgetary Educational Institution of Higher Education "Dagestan State Medical University" of the Ministry of Health of the Russian Federation

Kurbanalieva Zarema Abdullaevna

Federal State Budgetary Educational Institution of Higher Education "Dagestan State Medical University" of the Ministry of Health of the Russian Federation

Abdullaeva Leila Elmanovna

Federal State Budgetary Educational Institution of Higher Education "Dagestan State Medical University" of the Ministry of Health of the Russian Federation

Musaeva Ramilya Nadirovna

Federal State Budgetary Educational Institution of Higher Education "Dagestan State Medical University" of the Ministry of Health of the Russian Federation

Omarova Izabella Ruslanovna

Federal State Budgetary Educational Institution of Higher Education "Dagestan State Medical University" of the Ministry of Health of the Russian Federation

Dalgatov Sultan Inzhalupovich

Federal State Budgetary Educational Institution of Higher Education "Dagestan State Medical University" of the Ministry of Health of the Russian Federation

 

Omargadjieva Aminat Shamilovna

Federal State Budgetary Educational Institution of Higher Education "Dagestan State Medical University" of the Ministry of Health of the Russian Federation