Comparative Evaluation Of Antimicrobial Efficacy Of Morinda Citrifolia, Propolis, And Chlorhexidine Against Enterococcus Faecalis – An In Vitro Study”

Abstract

Dentistry has evolved significantly from a field that often considered extraction as the ultimate solution to one that emphasizes tooth preservation, thanks in large part to advancements like root canal therapy. This shift is driven by the recognition of microorganisms' central role in pulp and periapical diseases, challenging the dental community to effectively eliminate these pathogens from the complex root canal system. Despite advancements, the eradication of bacteria solely through mechanical means proves insufficient due to the root canal's intricate anatomy, making irrigation an indispensable part of endodontic therapy. The goal is to find an irrigant that is bactericidal, tissue-dissolving, smear layer-removing, and lubricating, yet non-irritating to healthy tissues.^{1, 2}

Root canal infections are notably caused by a diverse array of microorganisms, with over 600 species forming biofilms. Among these, Enterococcus faecalis is particularly prevalent and problematic, especially in secondary infections due to its resistance and virulence factors. E. faecalis is known for its ability to invade dentinal tubules and create biofilms, complicating the eradication process.³