Baboona (Matricaria Chamomilla): A Comprehensive Review of Its Unani And Modern Therapeutic Potential.

Main Article Content

Dr. Farkhunda Jabin
Dr. Wasi Akhtar

Abstract

Baboonah (Matricaria chamomilla), commonly known as chamomile, is a widely used medicinal plant in Unani Medicine for its calming, anti-inflammatory, and digestive properties. This review explores its botanical characteristics, traditional Unani uses, pharmacological activities, and current scientific evidence supporting its therapeutic applications. Matricaria chamomilla has shown promising potential in various conditions, including gastrointestinal disorders, sleep disturbances, and inflammatory diseases. This study aims to bridge traditional knowledge and modern pharmacological research, providing insights into its potential integration into contemporary therapeutic practices.

Article Details

How to Cite
Dr. Farkhunda Jabin, & Dr. Wasi Akhtar. (2023). Baboona (Matricaria Chamomilla): A Comprehensive Review of Its Unani And Modern Therapeutic Potential. Journal for ReAttach Therapy and Developmental Diversities, 6(9s), 2090–2096. https://doi.org/10.53555/jrtdd.v6i9s.3291
Section
Articles
Author Biographies

Dr. Farkhunda Jabin

Associate Professor, Department of Ilaj bit Tadbeer , School of Unani Medical Education and Research,  Jamia Hamdard  , New Delhi

Dr. Wasi Akhtar

Assistant Professor, Department of Moalajat , School of Unani Medical Education and Research,  Jamia Hamdard  , New Delhi

References

Ahmed Haqi Ismael, Haifa'Rasheed Muhsin and Kassim M. Sowdani, The analgesic effect of Local Passiflora, Cinnamon and Chamomile plant ethanol extract in Swiss albino mice, Kerbala journal of pharmaceutical sciences(July2017). No. (12),109-119.

Al-Hindawi MK, Al-Deen IH, Nabi MH, Ismail MA. Anti-inflammatory activity of some Iraqi plants using intact rats. J Ethnopharmacol 1989; 26(2):163-8.

Birt DF, Mitchell D, Gold B, Pour P, Pinch HC. Inhibition of ultraviolet light induced skincarcinogenesis in SKH-1 mice by apigenin, a plant flavonoid. Anticancer Res 1997;17:85–91.[PubMed: 9066634]

Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000; 7:273–282. [PubMed: 10969720]

Chopra RN, Nayar SL, Chopra IC, Glossary of Indian Medicinal Plants, National Institute of Science Communication and Information Resources(CSIR), New Delhi,1stedn and 6thReprint 2002,p162-163.

Carnat A, Carnat AP, Fraisse D, Ricoux L, Lamaison JL. The aromatic and polyphenolic composition of Roman chamomile tea. Fitoterapia 2004;75:32–38. [PubMed: 14693217]

Eddouks M, Lemhadri A, Zeggwah NA, Michel JB. Potent hypoglycaemic activity of the aqueous extract of chamaemelum nobile in normal and streptozotocin-induced diabetic rats. Diabetes Res Clin Pract 2005; 67:189–195. [PubMed: 15713350]26.

Evans S, Dizeyi N, Abrahamsson PA, Persson J. The effect of a novel botanical agent TBS-101 on invasive prostrate cancer in animal models. Anti Cancer Res 2009; 10:3917–3924.

Gates MA, Tworoger SS, Hecht JL, De Vivo I, Rosner B, Hankinson SE. A prospective study of dietary flavonoid intake and incidence of epithelial ovarian cancer. Int. J Cancer 2007; 121:2225–2232. [PubMed: 17471564]

Ghizlane Hajjaj et al. Anti-Inflammatory Evaluation of Aqueous Extract OfMatricaria Chamomilla L. (Asteraceae) In Experimental Animal Models from Morocco,World Journal of Pharmaceutical Research, Vol-2, Issue-5, 2013; pp1218-1228.

Glowania HJ, Raulin C, Swoboda M. Effect of chamomile on wound healing--a clinical doubleblind study. Z Hautkr 1987; 62:1267–1271

Gould L, Reddy CV, Gomprecht RF. Cardiac effects of chamomile tea. J Clin Pharmacol 1973; 11:475–479. [PubMed: 4490671]

Gupta et al. Pharmacological Potential of Matricaria recutita-A Review, International Journal of Pharmaceutical Sciences and Drug Research 2010; 2(1): 12-16 12

Hall I.H, Lee K.H, Stames C.O, Sumida Y, Wu R.Y, Wadell T.G, Cochran J.W, Gerhart K.G; J.Pharm. Sci. 1979, 68,537.

Hakeem M.A (1311). Bustanul Mufradat, Lucknow, Idara Taraqqi Urdu Publication

Hertog MG, Feskens EJ, Hollman PC, Katan MB, Kromhout D. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study. Lancet 1993; 342:1007–1011. [PubMed:8105262]

Ibn-e-Sina (1927) Al- Qanoon Fit Tibb: Urdu translation by Hakim. Seyyid Ghulam Husain Kanthoori, Vol 2, p 289.

Isaac O, Kristen G, Med. Welt 1980,31,1145.

Isaac O, Pharmacologycal investigations with compounds of chamomile, Planta Med; 1979, 35,118.

Jakovlev V, Isaac O, Thiemer K, Kunde R. Pharmacological investigations with Compounds of chamomile–II. New investigations on the antiphlogistic effects of (−)-α-bisabolol and bisabololoxides. Planta Med, 1979; 35: 125–140.

Jakovlev V, Isaac O, Flashamp E, Planta Med, 1983, 49, 67.

Kato A, Minoshima Y, Yamamoto J, Adachi I, Watson AA, Nash RJ. Protective effects of dietary Chamomile tea on diabetic complications. J Agric Food Chem 2008; 56:8206–8211. [PubMed:18681440]

Kassi E, Papoutsi Z, Fokialakis N, Messari I, Mitakou S, Moutsatsou P. Greek plant extracts Exhibit selective estrogen receptor modulator (SERM)-like properties. J Agric Food Chem 2004; 52:6956–6961. [PubMed: 15537303]

Kabiruddeen H, Makhzanul Mufradat Almaroof Khawazul Adviya pp 108-109.

Khayyal MT, Seif-El-Nasr M, El-Ghazaly MA, Okpanyi SN, Kelber O, Weiser D. Mechanisms Involved in the gastro-protective effect of STW 5 (Iberogast) and its components against ulcers and rebound acidity. Phytomedicine 2006; 13:56–66. [PubMed: 16963243]

Kirtikar KR, Basu BD, Indian Medicinal Plant 2nd edn Reprinted, Vol 2, (Lalit Mohan Basu, Allahabad )1987,pp1382-1384.

Kobayashi Y, Takahashi R, Ogino F Antipruritic effect of the single oral administration of German chamomile flower extract and its combined effect with antiallergic agents in ddY mice. J Ethnopharmacol 2005; 101(1-3):308-12.

Kroll U, Cordes C. Pharmaceutical prerequisites for a multi-target therapy. Phytomedicine 2006;5:12–19. [PubMed: 16857355]

Lemberkovics E, Kéry A, Marczal G, Simándi B, Szöke E. Phytochemical evaluation of essential oils, medicinal plants and their preparations. Acta Pharm Hung 1998;68:141–149. [PubMed9703700]

Lyseng-Williamson KA, Perry CM. Micronised purified flavonoid fraction: a review of its use in Chronic venous insufficiency, venous ulcers, and haemorrhoids. Drugs 2003; 63:71–100. [PubMed:12487623]56.

Lubhaya, R (1984) Goswami, Bayanul Adviya, New Delhi.

Medline Plus, US National Institutes of Health. 16 February 2012. Retrieved 30 August 2014.

Mann C, Staba E.J in Herbs, Spices and Medicinal plants. Recent Advances in Botany, Horticulture and Pharmacology [Craker L.E, Simon J.E.eds] 1986, Vol. 1 pp235-280).

McKay DL, Blumberg JB. A review of the bioactivity and potential health benefits of chamomile tea (Matricaria recutita L.). Phytother Res. 2006;20(7):519-30.

Merfort I, Heilmann J, Hagedorn-Leweke U, Lippold BC. In vivo skin penetration studies of chamomile flavones. Pharmazie 1994;49:509–511. [PubMed: 8073060]

Misra MC, Parshad R. Randomized clinical trial of micronized flavonoids in the early control of Bleeding from acute internal haemorrhoids. Br J Surg 2000; 87:868–872. [PubMed: 10931020]

Nadkarni AK, Indian Materia Medica-POPULAR PRAKASHAN PVT LTD- 1976_Reprint -1989,p772-773.

Nauman, I. T. Hamad, M. N. Husain, S. A. Comparative study of the analgesic activity of two Iraqi medicinal plants, Ruta graveolens and Matricaria chamomilla extracts. Pharmacologia 2012 Vol.3 No.11 pp.627-631 ref.16

Nissen HP, Blitz H, Kreyel HW. Prolifometrie, eine methode zur beurteilung der therapeutischen wirsamkeit kon Kamillosan®-Salbe. Z Hautkr 1988; 63:84–90.

Patel D, Shukla S, Gupta S. Apigenin and cancer chemoprevention: progress, potential and promise. Int J Oncol 2007; 30:233–245. [PubMed: 17143534]

Patzelt-Wenczler R, Ponce-Pöschl E. Proof of efficacy of Kamillosan(R) cream in atopic eczema.Eur. J Med Res 2000; 5:171–175. [PubMed: 10799352]

Rajpal V, Standardization of Botanicals Testing and Extraction Methods of Medicinal Herbs, 2nd edn, Vol-2,Business Horizons New Delhi 2011,pp216-228.

Ruhollah Shoara et,al Efficacy & Safety of Topical Chamomile oil for knee osteoarthritis “A Randomized Controlled Clinical Trial, Complementary Therapies in Clinical Practice Volume 21,Issue 3, August 2015,pp-181-187.

Sakai H, Misawa M. Effect of sodium azulene sulfonate on capsaicin-induced pharyngitis in rats.Basic Clinical Pharmacology Toxicology 2005;96:54–55. [PubMed: 15667596].

Saller R, Beschomer M, Hellenbrecht D. Dose dependency of symptomatic relief of complaints by chamomile steam inhalation in patients with common cold. Eur J Pharmacol 1990; 183:728–729.

Sepide Miraj and Samira Alesaeidi, A systematic review study of therapeutic effects of Matricaria recuitta chamomile (chamomile), Electronic Physician (ISSN: 2008-5842), September 2016, Volume: 8, Issue: 9, Pages: 3024-3031

Shipochliev T, Dimitrov A, Aleksandrova E. Anti-inflammatory action of a group of plant extracts] Vet Med Nauki. 1981; 18(6):87-94

Singh KG, Sarala Sonia and Nandini Konsoor, In-Vitro And Ex-Vivo Studies On The Antioxidant, Anti-Inflammatory And Antiarthritic Properties Of Camellia Sinensis, Hibiscus Rosa Sinensis, Matricaria Chamomilla, Rosa Sp., Zingiber officinale Tea Extracts, IJPSR (2018), Volume 9, Issue 8, 3543-3551

Shukla S, Mishra A, Fu P, MacLennan GT, Resnick MI, Gupta S. Up-regulation of insulin-like growth factor binding protein-3 by apigenin leads to growth inhibition and apoptosis of 22Rv1xenograft in athymic nude mice. FASEB J 2005; 19:2042–2044. [PubMed: 16230333]

Srivastava et al, A herbal medicine of the past with a bright future (Review), Molecular Medicine Reports, Mol Med Report. 2010 November 1; 3(6): 895–901. doi:10.3892/mmr.2010.377.

Standardisation of Single Drugs of Unani Medicine, Part-2, CCRUM, New Delhi, 1st edn, June-1992, pp141-147.

The Wealth of India, Dictionary of Indian Raw Materials and Industrial Products, National Institute of Science Communication(CSIR), New Delhi, 1st edn and Reprinted, Vol-6, 1998,pp308-309.

Uteshev BS, Laskova IL, Afanasev VA. [The immunomodulating activity of the heteropolysaccharides from German chamomile (Matricaria chamomilla) during air and immersion cooling Eksp Klin Farmakol 1999; 62(6):52-5.

Way TD, Kao MC, Lin JK. Apigenin induces apoptosis through proteasomal degradation of HER2/neu in HER2/neu-overexpressing breast cancer cells via the phosphatidylinositol-3'-kinase/Aktdependent pathway. J Biol Chem 2004; 279:4479–4489. [PubMed: 14602723]