Effectiveness of Liposomal Vitamin C on Postoperative Sequelae in Alveolar Osteitis: A Randomized Controlled Clinical Trial
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Abstract
Alveolar osteitis (AO), or dry socket, is a painful postoperative complication of tooth extraction, with higher prevalence in mandibular molar extractions. Conventional management addresses symptoms but lacks efficacy in improving tissue healing. This study evaluates the effect of liposomal Vitamin C as an adjunctive treatment for AO. A total of 93 patients with confirmed AO were randomized into a control group receiving standard care (n=46) and an experimental group receiving standard care plus 1,000 mg daily of liposomal Vitamin C (n=47). Primary outcome measured pain intensity, while secondary outcomes assessed healing time, swelling, and trismus. Results indicate that liposomal Vitamin C significantly reduced pain and accelerated healing compared to standard care alone (p < 0.05). Findings suggest liposomal Vitamin C as an effective adjunct therapy in AO management.
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References
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