Body Composition Alterations About Chronic Diseases: A Focus On Obesity And Diabetes
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Abstract
Numerous chronic diseases affect the metabolism system and the most common diseases include obesity and diabetes. Changes in body composition like obesity and reduced muscle mass are directly linked to these disorders. It helps to better understand the interconnections between body composition and biochemical parameters as well as to identify the metabolic derangements associated with obesity and diabetes. This study aimed to evaluate body mass index (BMI) and other anthropometric indices concerning Cancer and the underlying biochemical biomarkers in three groups, healthy controls, obese patients without diabetes, and obese patients with diabetes. The interactions between anthropometry, namely BMI, % body fat (BF), visceral fat, muscle mass, and bone mineral content (BMC), with biochemical markers, Fasting Blood Glucose (FBG), HbA1c, lipid profile, and triglycerides. In total 300 participants were included in the study, and 100 participants in each group. The obesity with diabetes group showed the highest FBG (142.3 ± 15.7 mg/dL) and HbA1c (7.8 ± 1.1%) compared to controls (FBG, 88. Fasting blood glucose as well, 127 ± 41 mg/dL, and HbA1c, 5.3 ± 0.4. Compared to controls, BMI was considerably higher among the obese groups: 33.2 ± 3.8 kg/m² for obesity only and 34.5 ± 4.2 kg/m² for obesity with diabetes. Obesity groups had the lowest muscle mass and BMC. Significant moderate significant correlations between %BF and FBG were found and MM was inversely correlated to HbA1c. These findings stress the need for individual targeted interventions to reduce metabolic risks.
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References
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