Investigation the Impact of Radiation and Physiotherapy Therapy on the Level of Cadmium in the Serum of Patients with Cancer

Abstract

Cancer is a devastating disease that continues to baffle doctors worldwide. While trace elements like cadmium (Cd) have been found to play various roles in the body, their involvement in cancer remains unclear. This study endeavored to analyze and compare the concentrations of specific elements in both the serum samples of cancer patients and those belonging to a control group, as well as with radiotherapy sessions.

A grand sum of 106 specimens were accumulated, comprising of 37 fit individuals and 69 cancer-afflicted patients. Following sample preparation, an atomic absorption spectrophotometer was employed to measure serum cadmium levels. The results showed that cadmium levels were significantly higher in cancer patients during sessions from 1 to 20 compared to healthy controls and the rest of the sessions.

The average concentration of cadmium in cancer patients without radiotherapy was found to be 9.033 ± 2.82, while it was 7.369 ± 1.025 for healthy individuals. The average cadmium concentrations varied in the patients group during the sessions. During sessions 1 to 10 days, the average cadmium concentration was 11.13 ± 1.57 (ppb). In sessions from 11 to 20 days, it increased to 11.83 ± 3.14 (ppb). Surprisingly, in the 21- to 30-day sessions, the average cadmium concentration decreased to 6.168 ± 0.79 (ppb). Finally, at sessions from 31 to 40 days, it decreased further to 5.955 ± 0.88 (ppb).

These findings suggest that exposure to radiotherapy in cancer patients may increase the level of cadmium concentration during sessions from 1 to 20 days. While the exact role of cadmium in cancer remains unclear, this study provides valuable insights into the potential impact of radiotherapy on cadmium levels in cancer patients. A complete comprehension of the connection between cadmium and cancer, as well as developing efficient treatment methods, requires additional investigation.