The Glutathion S-Transferasegene Polymorphisms in Automotive Technician

Abstract

the Glutathion S-Transferase  in human are an important detoxification enzymes which may be affected by different factors, the current work is a case control study consist of 32 Automotive Technician and 29 healthy individuals for GST types polymorphismsincluding (GSTT, GSTM and GSTP), the results found that GSTT null genotype was higher in Automotive Technician than control in significant differences (p 0.0300), the GSTM null genotyping didn’t find in Automotive Technician, while it found in (6.89%) of control group in non-significant differences (p 0.285). high percentage of GSTP null genotyping was recorded in control group than Automotive Technician group in non-significant differences (p 0.139).The present output found that there was an association of GSTT null genotyping with Automotive Technician, other GST types didn’t affect by this employment, further investigations may be suggested to detect other SNPs in GST genes.