Histological and Psychological Diagnosis Feature of Patients with Large Anaplastic Cells in Iraq

Abstract

The term ( ALCL) refers to anaplastic large cell lymphoma, which is one of the most aggressive cancerous diseases, non-Hodgkin's lymphoma of cells (T-cell) that show pathological characteristics but differ genetically in the period from March to August (2021) The researchers found in the data base of the Hematology Department of Al-Amal Specialist Hospital in The Cancer Center in Baghdad Governorate reported on cases diagnosed with lymphoma  The study included 10 biopsy samples from lymph nodes. All patients were males, with an average age ranging between 40-84 years. The study included other cases from another institution for the treatment of cancerous diseases, in addition to radiological procedures and pathological evaluation. The cases were diagnosed with this disease ( ALCL) based on pathology, radiography, and clinical examination. Evidence of lymphadenopathy was present in all the cases involved in the research. All cases had a biopsy of the lymph nodes, most of the axillary nodes were localized, and most cases of swelling were of diffuse or moderate type. The results showed positive examination ( CD30) for the sample and (ALK) and all patients had lymphadenopathy and all cases were positive for the examination (CD30) 100% and (ALK) 60 % while negative results 40% for (ALK) and (EMA) cases the majority in 20% and (EMA) the most common 40%. (ALCL) It is a lymphoma, cancerous, widespread and predatory, and there are effective therapeutic measures that reduce the toxicity of the patient in general. The type of lymphoid cells shows the extent of the spread of the disease and determines its type and severity, as the rays CT-SCAN show in order to determine the disease and its degree. Geographical area, race, age, gender and most of the cases were white with white skin that may be due to genetic factors or genetic mutations because they are more predisposed to mutations. The disease can be diagnosed by an experienced hematologist, but immunologically determined by factors or a group of immunological analyzes that were performed on the patient, and in conclusion( ALCL) considers highly virulent and predatory lymphomas and their early diagnosis is one of the important steps. Multiple cases of disease spread have been found to increase the ability to differentiate between groups of lymphocytes sub-groups (T cell) in order to better classify the sub-characteristics