“Phytochemical And Hypoglycemic Evaluation Of Artemisia Indica Willd Medicinal Plant”

Abstract

This study investigates the potential anti-diabetic effects of Artemisia indica, a herb that has been used for therapeutic purposes for centuries. A hydroalcoholic extract of Artemisia indica leaves, which are rich in terpenoids, alkaloids, and flavonoids, was shown to be safe for usage, according to studies that investigated acute toxicity. Experiments using rats that developed diabetes due to streptozotocin revealed that the extract has potent anti-diabetic properties. Treatment groups demonstrated significant improvements in oral glucose tolerance, greater serum insulin levels, and significantly lower fasting blood glucose levels in comparison to the control group, which was comprised of individuals with diabetes. In addition to the detection of increased insulin expression in beta cells, histological examination confirmed that the structure of the pancreatic islets had been conserved. In addition, the extract exhibited a significant level of antioxidant activity, and it also showed a reduction in oxidative stress indicators. The findings of this study indicate that Artemisia indica possesses both antioxidant and antihyperglycemic properties, which makes it a possible therapeutic alternative for the treatment of diabetes. Considering the potential of Artemisia indica as a natural anti-diabetic, there is a need for additional research into the molecular processes and therapeutic applications of this plant.