Comparative Study Of Triphala Ghrita Aschyotan And Hydroxy Propyl Methyl Cellulose Eye Drop In Dry Eye Syndrome.

Abstract

Dry eye is a disorder of the tear film which occurs due to tear deficiency or excessive tear evaporation; it causes damage to the interpalpebral ocular surface and is associated with a variety of symptoms reflecting ocular discomfort. Sushrutacharya described Shushkaakshipak vyadhi in vataj netrarogas as sadhya vyadhi in Uttartantra of Sushruta Samhita. It mainly causes shushkta in Netra.Considering the symptoms found in Shushkaakshipak it can be related to Dry eye Syndrome in modern science. Aschyotana is one of the Kriyakalpas described in Ayurveda. Aschyotana means instillation of eye drops. In Aschyotana procedure Acharya have described use of snigdha and madhur rasatmaka dravya in Vatapittajanya Vyadhi. As,Triphala Ghrita prepared for this study is vatta pittaghana, Chakshushya and having properties of snigdha guna and  is easily available.

Patients were randomly divided into two groups with 30 patients in each group. Trial group patients were treated with Triphala Ghrita two drops three times a day. Control group patients were treated with Hydroxy Propyl Methyl Cellulose eye drop, two drops three times a day.Follow up was done on 0^th, 15^th, 30^th, 45^th day for both group and observation were recorded in tabular form.For the assessment Subjective as well as objective criteria were taken.Subjective parameters viz. Dryness in eyes, Burning sensation in eyes, foreign sensation in eyes and objective parameters such as Schirmer’s test I and TFBUT were assessed.

In this study ,It was statistically analysed that Triphala Ghrita Aschyotan and Hydroxy propyl methyl cellulose(HPMC) eye drop have significant effects on all parameters of Dry eye syndrome. But Triphala ghrita Aschyotan is more effective than HPMC eye drop in all parameters of Dry eye syndrome.