Therapeutic Spectrum of Naushadar (Ammonium Chloride) in Unani Medicine: A Review of Evidence and Applications
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Abstract
Naushadar, or ammonium chloride, is a mineral-derived drug widely used in Unani medicine for its diverse pharmacological properties. Known by vernacular names such as Nausadar (Hindi) and Malah al Nar (Arabic), it is sourced naturally from mineral-rich springs and artificially through chemical processes. This review synthesizes its geographical distribution, chemical composition, traditional uses, and recent clinical and preclinical studies, particularly focusing on its role in compound formulations for acne vulgaris, post-inflammatory acne hyperpigmentation, dermatophytosis, hepatoprotective activity, melasma, and leucoderma. Despite its therapeutic potential, the lack of studies evaluating Naushadar as a single drug and other limitations highlight the need for further research. This paper aims to provide a comprehensive overview and identify future research directions to validate its efficacy and safety.
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References
Kabiruddin M. Makhzanul Mufredat (Kitabul Advia). 3rd ed. New Delhi: Idara Kitab us Shifa; 2014:409-10.
Hakeem HMA. Bustanul Mufradat. New Delhi: Idara Kitabul Shifa; 2002:594-95.
Nikhat S, Khan JA. Mufridat-e-Asri. 1st ed. New Delhi: Hidayat Publications and Distributors; 2020:394-95.
Ghani N. Khazainul Advia (Vol.1-2). 3rd ed. New Delhi: Idara Kitab us Shifa; 2011:1323-25.
Chughtai HNAT. Tajul Mufredat. 1st ed. New Delhi: Idara Kitab us Shifa; 2018:740.
Ali HSS. Unani Adviya Mufarrada. New Delhi: Director, Qaumi Council Baraye Farogh Urdu Zaban; 2013:316.
Ali HSSU. Unani Adviya Mufarrada. 4th ed. New Delhi: National Council for Promotion of Urdu Language; 2010. 316. ISBN: 978-81-7587-335-3.
Sultana S, Zulkifle M, Ansari AH, Shahnawaz. Efficacy of local application of a Unani formulation in acne vulgaris. Ancient Science of Life. 2015;35(2):124.
Sultana S, Shahnawaz, Ansari AH, Zulkifle M. Efficacy of an Unani formulation in reducing post-inflammatory acne hyperpigmentation marks: a clinical study. 2015. Available from: https://www.researchgate.net/publication/334989735_Efficacy_of_an_Unani_Formulation_in_Reducing_Post_Inflammatory_Acne_Hyperpigmentation_Marks-A_Clinical_Study.
Naseem S, Nawab M, Fatima SH, Minhajuddin A, Khan AA. Assessing the efficacy and safety of Unani pharmacopoeial formulations in dermatophytosis (quba)–a randomized controlled trial. Drug Metabolism and Personalized Therapy. 2022;38(2):169-77.
Khan N, Ahmed ST, Waheed MA, Uzma V, Ali Y, Rasheed NM et al.In vitro evaluation of antioxidant potential and in vivo studies for preclinical toxicity with hepatoprotective activity of Safoof-e-Akseer-e-Jigar. Int J Pharm Pharm Sci. 2017;6(8):2203-19.
Husain A, Ali A, Warsi MH, Rehman S, Ansari IA, Husain Set al. Clinical efficacy of a Unani formulation in the management of Sailan-ur-Rahem and Kasrat-e-Tams (leucorrhoea and menorrhagia). Asian Journal of Biomedical Research. 2021;27(3S):139-44. doi:10.53555/AJBR.v27i3S.2972.