A Clinical Evaluation Of Navaka Guggulu In The Management Of Medo Roga (Obesity)

Abstract

Medo Roga (Sthaulya) is a metabolic disorder described in Ayurveda as excessive accumulation of Meda Dhatu resulting from Kapha aggravation and Agni Mandya. It is closely correlated with obesity, a major global health issue associated with lifestyle, dietary excess, and metabolic imbalance. Navaka Guggulu, a classical Lekhana and Medohara formulation, is mentioned for managing disorders caused by Meda Dhatu Vriddhi. Aim: To evaluate the clinical efficacy of Navaka Guggulu in the management of Medo Roga (obesity). Materials and Methods: An open clinical study was conducted on 23 patients diagnosed with Medo Roga. Patients were administered Navaka Guggulu 4 g/day in divided doses with lukewarm water for 60 days. Shunthi Churna and Triphala Churna were given initially for Ama Pachana and Koshtha Shuddhi. Assessment was based on subjective parameters (Kshudha Atimatrata, Swedabadhata, Daurbalya, etc.) and objective parameters (Body Weight, BMI, WHR, SFT, and lipid profile). Follow-ups were done every 15 days. Results: Significant reductions were observed in body weight (↓3.81 kg), BMI (↓5.4%), serum cholesterol (↓14.2%), triglycerides (↓21.8%), LDL (↓16.8%), and VLDL (↓24.1%), along with an increase in HDL (↑19.2%). Clinically, 53.3% of patients showed marked improvement, 40% moderate improvement, and 6.6% mild improvement. No adverse reactions were reported. Conclusion: Navaka Guggulu demonstrated significant efficacy in reducing body weight and correcting lipid metabolism. Its Kapha-Medohara, Lekhana, and Srotoshodhaka actions contribute to its beneficial role in obesity management. The formulation is safe, effective, and can be integrated with dietary and lifestyle modifications for sustainable outcomes.