Nanoencapsulation of Withaferin-A for the Treatment of Neurological Disorder
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Abstract
A better delivery mechanism is ensured by a superior formulation. This study is based on the fact that people believe in natural products more than chemical products. Stress is a bad idea that has a detrimental impact on one's mental and physical health. In today's sedentary society, stress is very common. Drugs on the market are chemically produced and can have negative side effects. As a result, numerous studies have been conducted in order to uncover natural materials having anxiolytic characteristics, one of which is phytochemicals. Nanoparticles were used to try to encapsulate the phytochemical Withaferin-A. This phytochemical's bioavailability and water solubility are expected to improve when it is Nano encapsulated. The polymer Poly-(Lactic Acid) was used to Nano encapsulate Withaferin-A, and the creation of nanoparticles was discovered using the solvent displacement method. The concentration of loaded particles was determined using the diphenyl picrylhydrazyl assay.