The Relationship between Renal Impairment and Specific Laboratory Markers: A Comprehensive Investigation Focusing on Athletes.

Abstract

Background: Chronic kidney disease (CKD) is a notable public health issue that necessitates timely identification and efficient management to enhance patient outcomes. The primary objective of this study was to conduct a comprehensive investigation into the correlation between renal impairment and specific laboratory markers among athletes. The study included a total of 345 patients and 100 controls, making it a robust investigation. Special attention was paid to identifying potential biomarkers that could help predict renal impairment in athletes.

Results:The results showed that several laboratory markers were associated with an increased risk of renal impairment, including elevated levels of creatinine, urea, RBS, and cystatin C. Additionally, the study found that decreased levels of vitamin D3 and glomerular filtration rate (GFR) were significantly associated with renal impairment in athletes. 345 samples were collected from several hospitals in Baghdad (Al-Kadhimiya Teaching Hospital, Al-Yarmouk Teaching Hospital, and Neurological Hospital). In Addition, the results revealed strong correlations between RBS, Vitamin D3, Creatinine, Urea, Cystatin C levels, and GFR values. Specifically, negative correlations were observed for RBS (p < 0.001), creatinine (p < 0.001), urea (p < 0.001), cystatin C (p < 0.001), and Vitamin D3 (p < 0.001) as these markers increased, GFR values declined to signify impaired kidney function.

Conclusion: The study investigated the relationship between renal impairment and specific laboratory markers in athletes. Monitoring these parameters is crucial in identifying early signs of kidney disease that could aid in developing effective treatment strategies for managing CKD in athletes. Nonetheless, further research is needed to establish definitive causal relationships between these biomarkers and CKD progression.